Paired-end small RNA sequencing reveals a possible overestimation in the isomiR sequence repertoire previously reported from conventional single read data analysis

BACKGROUND: Next generation sequencing has allowed the discovery of miRNA isoforms, termed isomiRs. Some isomiRs are derived from imprecise processing of pre-miRNA precursors, leading to length variants. Additional variability is introduced by non-templated addition of bases at the ends or editing o...

Descripción completa

Detalles Bibliográficos
Autores principales: Sanchez Herrero, Jose Francisco, Pluvinet, Raquel, Luna de Haro, Antonio, Sumoy, Lauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8077951/
https://www.ncbi.nlm.nih.gov/pubmed/33902448
http://dx.doi.org/10.1186/s12859-021-04128-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8077951/
https://www.ncbi.nlm.nih.gov/pubmed/33902448
http://dx.doi.org/10.1186/s12859-021-04128-1

Ejemplares similares