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The Dynamic Partnership of Polycomb and Trithorax in Brain Development and Diseases
Epigenetic mechanisms, including DNA and histone modifications, are pivotal for normal brain development and functions by modulating spatial and temporal gene expression. Dysregulation of the epigenetic machinery can serve as a causal role in numerous brain disorders. Proper mammalian brain developm...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8078026/ https://www.ncbi.nlm.nih.gov/pubmed/33912356 http://dx.doi.org/10.3390/epigenomes3030017 |