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The Dynamic Partnership of Polycomb and Trithorax in Brain Development and Diseases

Epigenetic mechanisms, including DNA and histone modifications, are pivotal for normal brain development and functions by modulating spatial and temporal gene expression. Dysregulation of the epigenetic machinery can serve as a causal role in numerous brain disorders. Proper mammalian brain developm...

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Detalles Bibliográficos
Autores principales: Kuehner, Janise N., Yao, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8078026/
https://www.ncbi.nlm.nih.gov/pubmed/33912356
http://dx.doi.org/10.3390/epigenomes3030017