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Mycobacterium PPE31 Contributes to Host Cell Death

Genome scale mutagenesis identifies many genes required for mycobacterial infectivity and survival, but their contributions and mechanisms of action within the host are poorly understood. Using CRISPR interference, we created a knockdown of ppe31(Mm) gene in Mycobacterium marinum (M. marinum), which...

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Detalles Bibliográficos
Autores principales: Feng, Siyuan, Hong, Zhongsi, Zhang, Guoliang, Li, Jiachen, Tian, Guo-Bao, Zhou, Haibo, Huang, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8078103/
https://www.ncbi.nlm.nih.gov/pubmed/33928042
http://dx.doi.org/10.3389/fcimb.2021.629836