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Effects of HDAC4 on IL-1β-induced matrix metalloproteinase expression regulated partially through the WNT3A/β-catenin pathway

BACKGROUND: Histone deacetylase 4 (HDAC4) regulates chondrocyte hypertrophy and bone formation. The aim of the present study was to explore the effects of HDAC4 on Interleukin 1 beta (IL-1β)-induced chondrocyte extracellular matrix degradation and whether it is regulated through the WNT family membe...

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Detalles Bibliográficos
Autores principales: Ning, Qi, Gan, Ye-Hua, Shi, Rui-Rui, Meng, Juan-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8078302/
https://www.ncbi.nlm.nih.gov/pubmed/33840739
http://dx.doi.org/10.1097/CM9.0000000000001470