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Xrn1-resistant RNA structures are well-conserved within the genus flavivirus

Subgenomic RNAs are produced by several RNA viruses through incomplete degradation of their genomic RNA by the exoribonuclease Xrn1, and have been shown to be essential for viral growth and pathogenicity. Within the flavivirus genus of the Flaviviridae family, two distinct classes of Xrn1-resistant...

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Detalles Bibliográficos
Autores principales: Dilweg, Ivar W., Bouabda, Assia, Dalebout, Tim, Gultyaev, Alexander P., Bredenbeek, Peter J., Olsthoorn, R. C. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8078501/
https://www.ncbi.nlm.nih.gov/pubmed/33064973
http://dx.doi.org/10.1080/15476286.2020.1830238