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Astroglial Glutamine Synthetase and the Pathogenesis of Mesial Temporal Lobe Epilepsy

The enzyme glutamine synthetase (GS), also referred to as glutamate ammonia ligase, is abundant in astrocytes and catalyzes the conversion of ammonia and glutamate to glutamine. Deficiency or dysfunction of astrocytic GS in discrete brain regions have been associated with several types of epilepsy,...

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Detalles Bibliográficos
Autores principales: Sandhu, Mani Ratnesh S., Gruenbaum, Benjamin F., Gruenbaum, Shaun E., Dhaher, Roni, Deshpande, Ketaki, Funaro, Melissa C., Lee, Tih-Shih W., Zaveri, Hitten P., Eid, Tore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8078591/
https://www.ncbi.nlm.nih.gov/pubmed/33927688
http://dx.doi.org/10.3389/fneur.2021.665334