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Astroglial Glutamine Synthetase and the Pathogenesis of Mesial Temporal Lobe Epilepsy
The enzyme glutamine synthetase (GS), also referred to as glutamate ammonia ligase, is abundant in astrocytes and catalyzes the conversion of ammonia and glutamate to glutamine. Deficiency or dysfunction of astrocytic GS in discrete brain regions have been associated with several types of epilepsy,...
Autores principales: | Sandhu, Mani Ratnesh S., Gruenbaum, Benjamin F., Gruenbaum, Shaun E., Dhaher, Roni, Deshpande, Ketaki, Funaro, Melissa C., Lee, Tih-Shih W., Zaveri, Hitten P., Eid, Tore |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8078591/ https://www.ncbi.nlm.nih.gov/pubmed/33927688 http://dx.doi.org/10.3389/fneur.2021.665334 |
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