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Reliability of DNA methylation measures using Illumina methylation BeadChip

Illumina BeadChips are widely utilized in epigenome-wide association studies (EWAS). Several studies have reported that many probes on these arrays have poor reliability. Here, we compare different pre-processing methods to improve intra-class correlation coefficients (ICC). We describe the characte...

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Detalles Bibliográficos
Autores principales: Xu, Zongli, Taylor, Jack A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8078668/
https://www.ncbi.nlm.nih.gov/pubmed/32749174
http://dx.doi.org/10.1080/15592294.2020.1805692