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Safety and immunogenicity of an adjuvanted Escherichia coli adhesin vaccine in healthy women with and without histories of recurrent urinary tract infections: results from a first-in-human phase 1 study

Antibiotic resistance among gram-negative bacteria continues to rise globally at an alarming rate. New vaccines that prevent bacterial infections and reduce antibiotic use could provide a potential solution to these problems. This study focused on development of an investigational vaccine to prevent...

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Detalles Bibliográficos
Autores principales: Eldridge, Gary R., Hughey, Heidi, Rosenberger, Lois, Martin, Steven M., Shapiro, Andrew Marc, D’Antonio, Elizabeth, Krejci, Kent G., Shore, Neal, Peterson, James, Lukes, Andrea S., Starks, Courtney M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8078672/
https://www.ncbi.nlm.nih.gov/pubmed/33325785
http://dx.doi.org/10.1080/21645515.2020.1834807