Aicardi-Goutières syndrome-associated gene SAMHD1 preserves genome integrity by preventing R-loop formation at transcription–replication conflict regions

The comorbid association of autoimmune diseases with cancers has been a major obstacle to successful anti-cancer treatment. Cancer survival rate decreases significantly in patients with preexisting autoimmunity. However, to date, the molecular and cellular profiles of such comorbidities are poorly u...

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Detalles Bibliográficos
Autores principales: Park, Kiwon, Ryoo, Jeongmin, Jeong, Heena, Kim, Minsu, Lee, Sungwon, Hwang, Sung-Yeon, Ahn, Jiyoung, Kim, Doyeon, Moon, Hyungseok C., Baek, Daehyun, Kim, Kwangsoo, Park, Hye Yoon, Ahn, Kwangseog
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8078737/
https://www.ncbi.nlm.nih.gov/pubmed/33857133
http://dx.doi.org/10.1371/journal.pgen.1009523

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8078737/
https://www.ncbi.nlm.nih.gov/pubmed/33857133
http://dx.doi.org/10.1371/journal.pgen.1009523

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