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Extract of Scutellaria baicalensis induces semaphorin 3A production in human epidermal keratinocytes

In a disease-state-dependent manner, the histamine-resistant itch in dry skin-based skin diseases such as atopic dermatitis (AD) and xerosis is mainly due to hyperinnervation in the epidermis. Semaphorin 3A (Sema3A) is a nerve repulsion factor expressed in keratinocytes and it suppresses nerve fiber...

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Detalles Bibliográficos
Autores principales: Yoshioka, Yasuko, Kamata, Yayoi, Tominaga, Mitsutoshi, Umehara, Yoshie, Yoshida, Ikuyo, Matsuoka, Nobuya, Takamori, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8078742/
https://www.ncbi.nlm.nih.gov/pubmed/33905439
http://dx.doi.org/10.1371/journal.pone.0250663