Highly efficient CRISPR-Cas9-mediated gene knockout in primary human B cells for functional genetic studies of Epstein-Barr virus infection

Gene editing is now routine in all prokaryotic and metazoan cells but has not received much attention in immune cells when the CRISPR-Cas9 technology was introduced in the field of mammalian cell biology less than ten years ago. This versatile technology has been successfully adapted for gene modifi...

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Detalles Bibliográficos
Autores principales: Akidil, Ezgi, Albanese, Manuel, Buschle, Alexander, Ruhle, Adrian, Pich, Dagmar, Keppler, Oliver T., Hammerschmidt, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8078793/
https://www.ncbi.nlm.nih.gov/pubmed/33857265
http://dx.doi.org/10.1371/journal.ppat.1009117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8078793/
https://www.ncbi.nlm.nih.gov/pubmed/33857265
http://dx.doi.org/10.1371/journal.ppat.1009117

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