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Accurate contact-based modelling of repeat proteins predicts the structure of new repeats protein families

Repeat proteins are abundant in eukaryotic proteomes. They are involved in many eukaryotic specific functions, including signalling. For many of these proteins, the structure is not known, as they are difficult to crystallise. Today, using direct coupling analysis and deep learning it is often possi...

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Detalles Bibliográficos
Autores principales: Bassot, Claudio, Elofsson, Arne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8078820/
https://www.ncbi.nlm.nih.gov/pubmed/33857128
http://dx.doi.org/10.1371/journal.pcbi.1008798