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Accurate contact-based modelling of repeat proteins predicts the structure of new repeats protein families
Repeat proteins are abundant in eukaryotic proteomes. They are involved in many eukaryotic specific functions, including signalling. For many of these proteins, the structure is not known, as they are difficult to crystallise. Today, using direct coupling analysis and deep learning it is often possi...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8078820/ https://www.ncbi.nlm.nih.gov/pubmed/33857128 http://dx.doi.org/10.1371/journal.pcbi.1008798 |