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Cleavage of the vaspin N-terminus releases cell-penetrating peptides that affect early stages of adipogenesis and inhibit lipolysis in mature adipocytes

Vaspin expression and function is related to metabolic disorders and comorbidities of obesity. In various cellular and animal models of obesity, diabetes and atherosclerosis vaspin has shown beneficial, protective and/or compensatory action. While testing proteases for inhibition by vaspin, we notic...

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Detalles Bibliográficos
Autores principales: A. Tindall, Catherine, Erkner, Estelle, Stichel, Jan, G. Beck-Sickinger, Annette, Hoffmann, Anne, Weiner, Juliane, T. Heiker, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8078822/
https://www.ncbi.nlm.nih.gov/pubmed/33866927
http://dx.doi.org/10.1080/21623945.2021.1910154