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Cleavage of the vaspin N-terminus releases cell-penetrating peptides that affect early stages of adipogenesis and inhibit lipolysis in mature adipocytes
Vaspin expression and function is related to metabolic disorders and comorbidities of obesity. In various cellular and animal models of obesity, diabetes and atherosclerosis vaspin has shown beneficial, protective and/or compensatory action. While testing proteases for inhibition by vaspin, we notic...
Autores principales: | A. Tindall, Catherine, Erkner, Estelle, Stichel, Jan, G. Beck-Sickinger, Annette, Hoffmann, Anne, Weiner, Juliane, T. Heiker, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8078822/ https://www.ncbi.nlm.nih.gov/pubmed/33866927 http://dx.doi.org/10.1080/21623945.2021.1910154 |
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