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By Regulating the NLRP3 Inflammasome Can Reduce the Release of Inflammatory Factors in the Co-Culture Model of Tuberculosis H37Ra Strain and Rat Microglia

OBJECTIVE: Tuberculosis infection of the Central Nervous System can cause severe inflammation in microglia, and NLRP3 inflammasome is also an important source of inflammation in microglia. Therefore, in this study, we used a co-culture model of rat microglia and tuberculosis H37Ra strain to explore...

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Detalles Bibliográficos
Autores principales: Xie, Zhen, Hui, Hao, Yao, Qian, Duan, Yan, Li, Wu, Cheng, Ye, Zhang, Meng, Tian, Ye, Zhao, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8078893/
https://www.ncbi.nlm.nih.gov/pubmed/33928044
http://dx.doi.org/10.3389/fcimb.2021.637769