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GAF is essential for zygotic genome activation and chromatin accessibility in the early Drosophila embryo

Following fertilization, the genomes of the germ cells are reprogrammed to form the totipotent embryo. Pioneer transcription factors are essential for remodeling the chromatin and driving the initial wave of zygotic gene expression. In Drosophila melanogaster, the pioneer factor Zelda is essential f...

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Detalles Bibliográficos
Autores principales: Gaskill, Marissa M, Gibson, Tyler J, Larson, Elizabeth D, Harrison, Melissa M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079149/
https://www.ncbi.nlm.nih.gov/pubmed/33720012
http://dx.doi.org/10.7554/eLife.66668