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TGF-β-induced cell motility requires downregulation of ARHGAPs to sustain Rac1 activity
Transforming growth factor-β (TGF-β) signaling promotes cancer progression. In particular, the epithelial–mesenchymal transition (EMT) induced by TGF-β is considered crucial to the malignant phenotype of cancer cells. Here, we report that the EMT-associated cellular responses induced by TGF-β are me...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079281/ https://www.ncbi.nlm.nih.gov/pubmed/33741342 http://dx.doi.org/10.1016/j.jbc.2021.100545 |