Anticancer effects of radiation therapy combined with Polo-Like Kinase 4 (PLK4) inhibitor CFI-400945 in triple negative breast cancer

Development of novel multimodality radiotherapy treatments in metastatic breast cancer, especially in the most aggressive triple negative (TNBC) subtype, is of significant clinical interest. Here we show that a novel inhibitor of Polo-Like Kinase 4 (PLK4), CFI-400945, in combination with radiation,...

Descripción completa

Detalles Bibliográficos
Autores principales: Parsyan, Armen, Cruickshank, Jennifer, Hodgson, Kelsey, Wakeham, Drew, Pellizzari, Sierra, Bhat, Vasudeva, Cescon, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079282/
https://www.ncbi.nlm.nih.gov/pubmed/33866248
http://dx.doi.org/10.1016/j.breast.2021.03.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079282/
https://www.ncbi.nlm.nih.gov/pubmed/33866248
http://dx.doi.org/10.1016/j.breast.2021.03.011

Ejemplares similares