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EGFR (p. G719A+L747V)/EML4-ALK Co-alterations in Lung Adenocarcinoma with Leptomeningeal Metastasis Responding to Afatinib Treatment: A Case Report

Leptomeningeal metastasis (LM) is a disastrous complication of advanced lung adenocarcinoma (LAC) associated with poor prognosis and rapid deterioration of performance status. The prevalence of epidermal growth factor receptor (EGFR)/anaplastic lymphoma kinase (ALK) co-alterations in patients with L...

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Detalles Bibliográficos
Autores principales: Lu, Zhiqin, Wang, Xia, Luo, Yuxi, Wei, Jianping, Zeng, Zhimin, Xiong, Qiang, Cai, Jing, Liu, Anwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079359/
https://www.ncbi.nlm.nih.gov/pubmed/33935502
http://dx.doi.org/10.2147/OTT.S294635