Targeted transcriptome analysis using synthetic long read sequencing uncovers isoform reprograming in the progression of colon cancer

The characterization of human gene expression is limited by short read lengths, high error rates and large input requirements. Here, we used a synthetic long read (SLR) sequencing approach, LoopSeq, to generate accurate sequencing reads that span full length transcripts using standard short read dat...

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Detalles Bibliográficos
Autores principales: Liu, Silvia, Wu, Indira, Yu, Yan-Ping, Balamotis, Michael, Ren, Baoguo, Ben Yehezkel, Tuval, Luo, Jian-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079361/
https://www.ncbi.nlm.nih.gov/pubmed/33907296
http://dx.doi.org/10.1038/s42003-021-02024-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079361/
https://www.ncbi.nlm.nih.gov/pubmed/33907296
http://dx.doi.org/10.1038/s42003-021-02024-1

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