Metabolic adaptations to hypoxia in the neonatal mouse forebrain can occur independently of the transporters SLC7A5 and SLC3A2

Neonatal encephalopathy due to hypoxia–ischemia is associated with adverse neurodevelopmental effects. The involvement of branched chain amino acids (BCAAs) in this is largely unexplored. Transport of BCAAs at the plasma membrane is facilitated by SLC7A5/SLC3A2, which increase with hypoxia. We hypot...

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Detalles Bibliográficos
Autores principales: Fitzgerald, Eamon, Roberts, Jennie, Tennant, Daniel A., Boardman, James P., Drake, Amanda J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079390/
https://www.ncbi.nlm.nih.gov/pubmed/33907288
http://dx.doi.org/10.1038/s41598-021-88757-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079390/
https://www.ncbi.nlm.nih.gov/pubmed/33907288
http://dx.doi.org/10.1038/s41598-021-88757-9

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