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Metabolic adaptations to hypoxia in the neonatal mouse forebrain can occur independently of the transporters SLC7A5 and SLC3A2
Neonatal encephalopathy due to hypoxia–ischemia is associated with adverse neurodevelopmental effects. The involvement of branched chain amino acids (BCAAs) in this is largely unexplored. Transport of BCAAs at the plasma membrane is facilitated by SLC7A5/SLC3A2, which increase with hypoxia. We hypot...
Autores principales: | Fitzgerald, Eamon, Roberts, Jennie, Tennant, Daniel A., Boardman, James P., Drake, Amanda J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079390/ https://www.ncbi.nlm.nih.gov/pubmed/33907288 http://dx.doi.org/10.1038/s41598-021-88757-9 |
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