Cell-type-specific expression quantitative trait loci associated with Alzheimer disease in blood and brain tissue

Because regulation of gene expression is heritable and context-dependent, we investigated AD-related gene expression patterns in cell types in blood and brain. Cis-expression quantitative trait locus (eQTL) mapping was performed genome-wide in blood from 5257 Framingham Heart Study (FHS) participant...

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Detalles Bibliográficos
Autores principales: Patel, Devanshi, Zhang, Xiaoling, Farrell, John J., Chung, Jaeyoon, Stein, Thor D., Lunetta, Kathryn L., Farrer, Lindsay A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079392/
https://www.ncbi.nlm.nih.gov/pubmed/33907181
http://dx.doi.org/10.1038/s41398-021-01373-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079392/
https://www.ncbi.nlm.nih.gov/pubmed/33907181
http://dx.doi.org/10.1038/s41398-021-01373-z

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