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Cell-type-specific expression quantitative trait loci associated with Alzheimer disease in blood and brain tissue
Because regulation of gene expression is heritable and context-dependent, we investigated AD-related gene expression patterns in cell types in blood and brain. Cis-expression quantitative trait locus (eQTL) mapping was performed genome-wide in blood from 5257 Framingham Heart Study (FHS) participant...
Autores principales: | Patel, Devanshi, Zhang, Xiaoling, Farrell, John J., Chung, Jaeyoon, Stein, Thor D., Lunetta, Kathryn L., Farrer, Lindsay A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079392/ https://www.ncbi.nlm.nih.gov/pubmed/33907181 http://dx.doi.org/10.1038/s41398-021-01373-z |
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