Phagocytic and pinocytic uptake of cholesterol in Tetrahymena thermophila impact differently on gene regulation for sterol homeostasis

The ciliate Tetrahymena thermophila can either synthesize tetrahymanol or when available, assimilate and modify sterols from its diet. This metabolic shift is mainly driven by transcriptional regulation of genes for tetrahymanol synthesis (TS) and sterol bioconversion (SB). The mechanistic details o...

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Detalles Bibliográficos
Autores principales: Hernández, Josefina, Gabrielli, Matías, Costa, Joaquín, Uttaro, Antonio D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079401/
https://www.ncbi.nlm.nih.gov/pubmed/33907281
http://dx.doi.org/10.1038/s41598-021-88737-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079401/
https://www.ncbi.nlm.nih.gov/pubmed/33907281
http://dx.doi.org/10.1038/s41598-021-88737-z

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