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A simple method to measure sulfonation in man using paracetamol as probe drug

Sulfotransferase enzymes (SULT) catalyse sulfoconjugation of drugs, as well as endogenous mediators, gut microbiota metabolites and environmental xenobiotics. To address the limited evidence on sulfonation activity from clinical research, we developed a clinical metabolic phenotyping method using pa...

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Detalles Bibliográficos
Autores principales: Marto, Natália, Morello, Judit, Antunes, Alexandra M. M., Azeredo, Sofia, Monteiro, Emília C., Pereira, Sofia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079418/
https://www.ncbi.nlm.nih.gov/pubmed/33907224
http://dx.doi.org/10.1038/s41598-021-88393-3