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A simple method to measure sulfonation in man using paracetamol as probe drug
Sulfotransferase enzymes (SULT) catalyse sulfoconjugation of drugs, as well as endogenous mediators, gut microbiota metabolites and environmental xenobiotics. To address the limited evidence on sulfonation activity from clinical research, we developed a clinical metabolic phenotyping method using pa...
Autores principales: | Marto, Natália, Morello, Judit, Antunes, Alexandra M. M., Azeredo, Sofia, Monteiro, Emília C., Pereira, Sofia A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079418/ https://www.ncbi.nlm.nih.gov/pubmed/33907224 http://dx.doi.org/10.1038/s41598-021-88393-3 |
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