Phosphopeptide interactions of the Nbs1 N-terminal FHA-BRCT1/2 domains

Human Nbs1, a component of the MRN complex involved in DNA double strand break repair, contains a concatenated N-terminal FHA-BRCT1/2 sequence that supports interaction with multiple phosphopeptide binding partners. MDC1 binding localizes Nbs1 to the damage site, while binding of CDK-phosphorylated...

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Detalles Bibliográficos
Autores principales: Kim, Kyungmin, Kirby, Thomas W., Perera, Lalith, London, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079451/
https://www.ncbi.nlm.nih.gov/pubmed/33907233
http://dx.doi.org/10.1038/s41598-021-88400-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079451/
https://www.ncbi.nlm.nih.gov/pubmed/33907233
http://dx.doi.org/10.1038/s41598-021-88400-7

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