Endogenous Opioid Levels Do Not Correlate With Itch Intensity and Therapeutic Interventions in Hepatic Pruritus

Background: Chronic pruritus affects up to 70% of patients with immune-mediated hepatobiliary disorders. Antagonists of the μ-opioid receptor (MOR) and agonists of the κ-opioid receptor (KOR) are used to treat hepatic itch, albeit with limited success. An imbalance between ligands of MOR and KOR rec...

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Detalles Bibliográficos
Autores principales: Düll, Miriam M., Wolf, Katharina, Vetter, Marcel, Dietrich, Peter, Neurath, Markus F., Kremer, Andreas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079640/
https://www.ncbi.nlm.nih.gov/pubmed/33937284
http://dx.doi.org/10.3389/fmed.2021.641163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079640/
https://www.ncbi.nlm.nih.gov/pubmed/33937284
http://dx.doi.org/10.3389/fmed.2021.641163

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