Cargando…

Regulation of Intrinsic and Bystander T Follicular Helper Cell Differentiation and Autoimmunity by Tsc1

T Follicular helper (Tfh) cells promote germinal center (GC) B cell responses to develop effective humoral immunity against pathogens. However, dysregulated Tfh cells can also trigger autoantibody production and the development of autoimmune diseases. We report here that Tsc1, a regulator for mTOR s...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Shimeng, Li, Lei, Xie, Danli, Reddy, Srija, Sleasman, John W., Ma, Li, Zhong, Xiao-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079652/
https://www.ncbi.nlm.nih.gov/pubmed/33936036
http://dx.doi.org/10.3389/fimmu.2021.620437