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CpG-ODN induced antimicrobial immunity in neonatal chicks involves a substantial shift in serum metabolic profiles

Synthetic CpG-ODNs can promote antimicrobial immunity in neonatal chicks by enriching immune compartments and activating immune cells. Activated immune cells undergo profound metabolic changes to meet cellular biosynthesis and energy demands and facilitate the signaling processes. We hypothesize tha...

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Detalles Bibliográficos
Autores principales: Goonewardene, Kalhari Bandara, Karu, Naama, Ahmed, Khawaja Ashfaque, Popowich, Shelly, Chow-Lockerbie, Betty, Ayalew, Lisanework E., Karunarathna, Ruwani, Gunawardana, Thushari, Liu, Mengying, Tikoo, Suresh K., Foldvari, Marianna, Willson, Philip, Mandal, Rupasri, Wishart, David S., Gomis, Susantha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079682/
https://www.ncbi.nlm.nih.gov/pubmed/33907214
http://dx.doi.org/10.1038/s41598-021-88386-2