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Antibodies against apoB100 peptide 210 inhibit atherosclerosis in apoE(-/-) mice

Atherosclerotic plaques are characterized by an accumulation and subsequent oxidation of LDL, resulting in adaptive immune responses against formed or exposed neoepitopes of the LDL particle. Autoantibodies against native p210, the 3136–3155 amino acid sequence of the LDL protein apolipoprotein B-10...

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Detalles Bibliográficos
Autores principales: Dunér, Pontus, Mattisson, Ingrid Yao, Fogelstrand, Per, Glise, Lars, Ruiz, Stacey, Farina, Christopher, Borén, Jan, Nilsson, Jan, Bengtsson, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079692/
https://www.ncbi.nlm.nih.gov/pubmed/33907226
http://dx.doi.org/10.1038/s41598-021-88430-1