Mitochondrial DNA impact on joint damaged process in a conplastic mouse model after being surgically induced with osteoarthritis

It has been suggested that mitochondrial dysfunction and mtDNA variations may contribute to osteoarthritis (OA) pathogenesis. However, the causative link to support this claim is lacking. Here, we surgically-induced OA in conplastic mice in order to evaluate the functional consequences of mtDNA hapl...

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Detalles Bibliográficos
Autores principales: Scotece, Morena, Rego-Pérez, Ignacio, Lechuga-Vieco, Ana Victoria, Cortés, Alberto Centeno, Jiménez-Gómez, María Concepción, Filgueira-Fernández, Purificación, Vaamonde-García, Carlos, Enríquez, José Antonio, Blanco, Francisco J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079696/
https://www.ncbi.nlm.nih.gov/pubmed/33907208
http://dx.doi.org/10.1038/s41598-021-88083-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079696/
https://www.ncbi.nlm.nih.gov/pubmed/33907208
http://dx.doi.org/10.1038/s41598-021-88083-0

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