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Transcriptional signatures in prefrontal cortex confer vulnerability versus resilience to food and cocaine addiction-like behavior

Addiction is a chronic relapsing brain disease characterized by compulsive reward-seeking despite harmful consequences. The mechanisms underlying addiction are orchestrated by transcriptional reprogramming in the reward system of vulnerable subjects. This study aims at revealing gene expression alte...

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Detalles Bibliográficos
Autores principales: Navandar, Mohit, Martín-García, Elena, Maldonado, Rafael, Lutz, Beat, Gerber, Susanne, Ruiz de Azua, Inigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079697/
https://www.ncbi.nlm.nih.gov/pubmed/33907201
http://dx.doi.org/10.1038/s41598-021-88363-9