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Colorimetric RT-LAMP SARS-CoV-2 diagnostic sensitivity relies on color interpretation and viral load

The use of RT-LAMP (reverse transcriptase—loop mediated isothermal amplification) has been considered as a promising point-of-care method to diagnose COVID-19. In this manuscript we show that the RT-LAMP reaction has a sensitivity of only 200 RNA virus copies, with a color change from pink to yellow...

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Detalles Bibliográficos
Autores principales: Aoki, Mateus Nóbrega, de Oliveira Coelho, Bruna, Góes, Luiz Gustavo Bentim, Minoprio, Paola, Durigon, Edison Luiz, Morello, Luis Gustavo, Marchini, Fabricio Klerynton, Riediger, Irina Natassja, do Carmo Debur, Maria, Nakaya, Helder I., Blanes, Lucas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079700/
https://www.ncbi.nlm.nih.gov/pubmed/33907239
http://dx.doi.org/10.1038/s41598-021-88506-y