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Carnitine/organic cation transporter 1 precipitates the progression of interstitial fibrosis through oxidative stress in diabetic nephropathy in mice

Carnitine/organic cation transporter 1 (OCTN1) is the only known uptake transporter for ergothioneine which is a food-derived strong antioxidant amino acid that is absorbed by OCTN1. We previously reported the roles of OCTN1/ergothioneine in the progression of kidney fibrosis in ischemic kidney dise...

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Detalles Bibliográficos
Autores principales: Makiishi, Shohei, Furuichi, Kengo, Yamamura, Yuta, Sako, Keisuke, Shinozaki, Yasuyuki, Toyama, Tadashi, Kitajima, Shinji, Iwata, Yasunori, Sakai, Norihiko, Shimizu, Miho, Hirose-Sugiura, Tomoko, Kaneko, Shuichi, Kato, Yukio, Wada, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079701/
https://www.ncbi.nlm.nih.gov/pubmed/33907247
http://dx.doi.org/10.1038/s41598-021-88724-4