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Ulcerative colitis immune cell landscapes and differentially expressed gene signatures determine novel regulators and predict clinical response to biologic therapy

The heterogeneous pathobiology underlying Ulcerative Colitis (UC) is not fully understood. Using publicly available transcriptomes from adult UC patients, we identified the immune cell landscape, molecular pathways, and differentially expressed genes (DEGs) across patient cohorts and their associati...

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Detalles Bibliográficos
Autores principales: Penrose, Harrison M., Iftikhar, Rida, Collins, Morgan E., Toraih, Eman, Ruiz, Emmanuelle, Ungerleider, Nathan, Nakhoul, Hani, Flemington, Erik F., Kandil, Emad, Shah, Shamita B., Savkovic, Suzana D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079702/
https://www.ncbi.nlm.nih.gov/pubmed/33907256
http://dx.doi.org/10.1038/s41598-021-88489-w