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Ulcerative colitis immune cell landscapes and differentially expressed gene signatures determine novel regulators and predict clinical response to biologic therapy
The heterogeneous pathobiology underlying Ulcerative Colitis (UC) is not fully understood. Using publicly available transcriptomes from adult UC patients, we identified the immune cell landscape, molecular pathways, and differentially expressed genes (DEGs) across patient cohorts and their associati...
Autores principales: | Penrose, Harrison M., Iftikhar, Rida, Collins, Morgan E., Toraih, Eman, Ruiz, Emmanuelle, Ungerleider, Nathan, Nakhoul, Hani, Flemington, Erik F., Kandil, Emad, Shah, Shamita B., Savkovic, Suzana D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079702/ https://www.ncbi.nlm.nih.gov/pubmed/33907256 http://dx.doi.org/10.1038/s41598-021-88489-w |
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