Hedgehog interacting protein (HHIP) represses airway remodeling and metabolic reprogramming in COPD-derived airway smooth muscle cells

Although HHIP locus has been consistently associated with the susceptibility to COPD including airway remodeling and emphysema in genome-wide association studies, the molecular mechanism underlying this genetic association remains incompletely understood. By utilizing Hhip(+/-) mice and primary huma...

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Detalles Bibliográficos
Autores principales: Li, Yan, Zhang, Li, Polverino, Francesca, Guo, Feng, Hao, Yuan, Lao, Taotao, Xu, Shuang, Li, Lijia, Pham, Betty, Owen, Caroline A., Zhou, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079715/
https://www.ncbi.nlm.nih.gov/pubmed/33907231
http://dx.doi.org/10.1038/s41598-021-88434-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079715/
https://www.ncbi.nlm.nih.gov/pubmed/33907231
http://dx.doi.org/10.1038/s41598-021-88434-x

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