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Accelerated Bone Regeneration by Adrenomedullin 2 Through Improving the Coupling of Osteogenesis and Angiogenesis via β-Catenin Signaling

Both osteogenic differentiation and the pro-angiogenic potential of bone marrow mesenchymal stem cells (BMSCs) contribute to bone regeneration during distraction osteogenesis (DO). Adrenomedullin 2 (ADM2), an endogenous bioactive peptide belonging to the calcitonin gene-related peptide family, exhib...

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Detalles Bibliográficos
Autores principales: Wang, Feng, Wang, Wenbo, Kong, Lingchi, Shi, Li, Wang, Mengwei, Chai, Yimin, Xu, Jia, Kang, Qinglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079771/
https://www.ncbi.nlm.nih.gov/pubmed/33937244
http://dx.doi.org/10.3389/fcell.2021.649277