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Context-dependent and -independent selection on synonymous mutations revealed by 1,135 genomes of Arabidopsis thaliana

BACKGROUND: Synonymous mutations do not alter the amino acids and therefore are regarded as neutral for a long time. However, they do change the tRNA adaptation index (tAI) of a particular codon (independent of its context), affecting the tRNA availability during translation. They could also change...

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Detalles Bibliográficos
Autores principales: Chu, Duan, Wei, Lai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079846/
https://www.ncbi.nlm.nih.gov/pubmed/33910528
http://dx.doi.org/10.1186/s12862-021-01792-y