Inhibition of TMEM16A by Natural Product Silibinin: Potential Lead Compounds for Treatment of Lung Adenocarcinoma

Background: Effective anticancer therapy can be achieved by identifying novel tumor-specific drug targets and screening of new drugs. Recently, TMEM16A has been identified to be overexpressed in lung adenocarcinoma, and inhibitors of TMEM16A showed obvious antitumor efficacy. Methods: YFP fluorescen...

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Detalles Bibliográficos
Autores principales: Guo, Shuai, Bai, Xue, Liu, Yufei, Shi, Sai, Wang, Xuzhao, Zhan, Yong, Kang, Xianjiang, Chen, Yafei, An, Hailong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079988/
https://www.ncbi.nlm.nih.gov/pubmed/33935737
http://dx.doi.org/10.3389/fphar.2021.643489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079988/
https://www.ncbi.nlm.nih.gov/pubmed/33935737
http://dx.doi.org/10.3389/fphar.2021.643489

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