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Inhibition of TMEM16A by Natural Product Silibinin: Potential Lead Compounds for Treatment of Lung Adenocarcinoma
Background: Effective anticancer therapy can be achieved by identifying novel tumor-specific drug targets and screening of new drugs. Recently, TMEM16A has been identified to be overexpressed in lung adenocarcinoma, and inhibitors of TMEM16A showed obvious antitumor efficacy. Methods: YFP fluorescen...
Autores principales: | Guo, Shuai, Bai, Xue, Liu, Yufei, Shi, Sai, Wang, Xuzhao, Zhan, Yong, Kang, Xianjiang, Chen, Yafei, An, Hailong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079988/ https://www.ncbi.nlm.nih.gov/pubmed/33935737 http://dx.doi.org/10.3389/fphar.2021.643489 |
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