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Transcriptional firing represses bactericidal activity in cystic fibrosis airway neutrophils
Neutrophils are often considered terminally differentiated and poised for bacterial killing. In chronic diseases such as cystic fibrosis (CF), an unexplained paradox pits massive neutrophil presence against prolonged bacterial infections. Here, we show that neutrophils recruited to CF airways in viv...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080108/ https://www.ncbi.nlm.nih.gov/pubmed/33948572 http://dx.doi.org/10.1016/j.xcrm.2021.100239 |