Transcriptional firing represses bactericidal activity in cystic fibrosis airway neutrophils

Neutrophils are often considered terminally differentiated and poised for bacterial killing. In chronic diseases such as cystic fibrosis (CF), an unexplained paradox pits massive neutrophil presence against prolonged bacterial infections. Here, we show that neutrophils recruited to CF airways in viv...

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Detalles Bibliográficos
Autores principales: Margaroli, Camilla, Moncada-Giraldo, Diego, Gulick, Dalia Arafat, Dobosh, Brian, Giacalone, Vincent D., Forrest, Osric A., Sun, Fangxu, Gu, Chunhui, Gaggar, Amit, Kissick, Haydn, Wu, Ronghu, Gibson, Greg, Tirouvanziam, Rabindra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080108/
https://www.ncbi.nlm.nih.gov/pubmed/33948572
http://dx.doi.org/10.1016/j.xcrm.2021.100239

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