Serotypic evolution of measles virus is constrained by multiple co-dominant B cell epitopes on its surface glycoproteins

After centuries of pestilence and decades of global vaccination, measles virus (MeV) genotypes capable of evading vaccine-induced immunity have not emerged. Here, by systematically building mutations into the hemagglutinin (H) glycoprotein of an attenuated measles virus strain and assaying for serum...

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Detalles Bibliográficos
Autores principales: Muñoz-Alía, Miguel Ángel, Nace, Rebecca A., Zhang, Lianwen, Russell, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080110/
https://www.ncbi.nlm.nih.gov/pubmed/33948566
http://dx.doi.org/10.1016/j.xcrm.2021.100225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080110/
https://www.ncbi.nlm.nih.gov/pubmed/33948566
http://dx.doi.org/10.1016/j.xcrm.2021.100225

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