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Serotypic evolution of measles virus is constrained by multiple co-dominant B cell epitopes on its surface glycoproteins
After centuries of pestilence and decades of global vaccination, measles virus (MeV) genotypes capable of evading vaccine-induced immunity have not emerged. Here, by systematically building mutations into the hemagglutinin (H) glycoprotein of an attenuated measles virus strain and assaying for serum...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080110/ https://www.ncbi.nlm.nih.gov/pubmed/33948566 http://dx.doi.org/10.1016/j.xcrm.2021.100225 |