SH2B3, Transcribed by STAT1, Promotes Glioblastoma Progression Through Transducing IL-6/gp130 Signaling to Activate STAT3 Signaling

Glioblastoma (GBM) is the most common and aggressive brain tumor in adults. The aberrant activation of STAT3 commonly occurs in GBM and is a key player in GBM tumorigenesis. Yet, the aberrant activation of STAT3 signaling is not fully understood. Here, we report that SH2B adaptor protein 3 (SH2B3) i...

Descripción completa

Detalles Bibliográficos
Autores principales: Cai, Shan, Lu, Jian-xiang, Wang, Yan-pei, Shi, Chao-jia, Yuan, Tian, Wang, Xiang-peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080264/
https://www.ncbi.nlm.nih.gov/pubmed/33937225
http://dx.doi.org/10.3389/fcell.2021.606527

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080264/
https://www.ncbi.nlm.nih.gov/pubmed/33937225
http://dx.doi.org/10.3389/fcell.2021.606527

Ejemplares similares